Carly is a 9 month who is brought in by her parents as she has been unsettled and not feeding well for the last day or so. Her obs at triage show a puls of 277 and she is brought straight round to resus.Her ECG is as follows:
This post is based on several resources but in particular from Donovan Dwyer’s talk at DFTB17.
What happens in a normal heart?The sino-atrial (SA) node is the pacemaker of the heart. It is situated in the right atrium and it generates an electrical impulse that conducts through the whole heart and causes it to contract. The impulses from the SA node, travels to the atrioventricular (AV node). The AV node slows the current (0.1 second pause) and then allows it to pass through the ventricles (via the Bundle of His and the Purkinje fibres). This process allows the atria to contract fully and then allows the ventricles to contract from base to apex.
What changes this in SVT?SVT is usually caused by a re-entrant circuit. In this case a second impulses is triggered before the normal impulse has been fully conducted through the AV node and the tracts reset. This happens where there is increased automaticity in the atrium causing an impulses (from fever, stretch, stimulation etc). This stimulates the AV node when one part of the tract is refractory. The fast pathway has a longer refractory time, so while the slow pathway may be working again, the fast pathway is in its refractory period. From Donovan Dwyer’s DFTB17 talk So the impulse goes down the slow tract and is blocked down the fast tract. By the time is reaches the end of the AV node, the refractory period has passed, and it is now able to travel back up the fast pathway.
How do we treat this?The goal of treatment is to stop conduction through the AV node for long enough that the SA node will take over as the primary pacemaker. We can do this in ED physiologically or medically. Importantly – make sure you are recording a rhythm strip while you try to revert the ECG as the cardiologists will need to see this.
Physiological treatmentThe first thing to try is to physiologically revert the SVT. This can be done using valsalva in older children by blowing into a pipe/syringe. This can be blowing into a pipe attached to a sphygmomanometer to hit 40mmHg for a sustained 15 seconds. Or patients can blow into a 10ml syringe and aim to start moving the plunger. Both are effective. This works because the extra squeeze on the heart increases the cardiac output and increased carotid and baroreceptor stimulus increasing the BP in the initial stage. After the pressure is sustained, blood volume is forced into the legs and head (causing neck vein distension). The drop in preload means the atrium is stimulated and the heart pumps harder and faster to make up for it, and the blood pressure drops. At the end of the manoeuvre, there is a sudden release, and all the blood flows into the heart causing a huge flow of blood into the carotid and baroreceptors leading to vagal inhibition. Using a modified valsalva works better – if you lift the patients legs in the air and lie then flat immediately after the release, you will increase the venous return and improve the chances of reversion. The REVERT study showed that this method reverted SVT in 43% (vs 17%) of (adult) patients. The diving reflex is another version of this. Young infants cannot do a valsalva manoeuvre (although it can happen when they cry). The diving reflex causes vasoconstriction. It does this because your hands, feet, and face have ten times the heat and cold receptors of the rest of your body. They act to protect you. When you jump into cold water you vasoconstrict to preserve heat at your core. There is a massive shunt of blood to your central circulation that your heart has to manage pumping into your lungs, and that causes you to take a deep breath. When you put a baby into a cold environment, they get profound vasoconstriction in the same way, and blood is shunted to the core. You do, however, need a well-functioning heart for this to work – all the blood that returns needs to be pumped out effectively. This is a potential problem in adults with heart failure. In children with heart failure there is a second pathway – this goes through facial stimulation of cold blood to the hypothalamus. This causes the heart to slow down and decrease metabolism. Because of this, children in heart failure may still respond to the diving reflex (whereas adults will not). You can use a face mask submerged in ice cold water which is put onto the baby’s face for 30-40 seconds – this is as effective as dunking them in a bucket of ice and a lot more kind.
Medical treatmentAdenosine is our first line medical treatment for SVT. It opens the potassium channels briefly and depolarises the AV node – aiming to break the circuit and for the SA node to take over. It only has a half life of 10 seconds. Start with 100mcg/kg as the first dose and then increase to a max of 500mcg/kg (less in neonates). There are five outcomes for what might happen when you give adenosine.
ReversionThis is what we all hope for where the patient returns to sinus rhythm. Often there is a recovery tachycardia due to a net deoxygenation from being tachycardic for so long. All children with SVT, even if they revert need cardiology follow up. This is to determine any underlying cause, but also for prophylaxis. Children (particularly infants) cannot tell us when they are in SVT and they may present after several days. Prophylaxis aims to prevent them presenting in collapse or failure.
No responseIt’s happened to all of us. When the adenosine doesn’t work, consider the 5 Ds.
- Delivery: remember that it only has a 10 second half life. Give it through a cannula in a large vein, with the arm up in the air, using a three-way tap to ensure a fast bolus and a flush straight after the adenosine.
- Distance: are you giving it through a cannula in the arm, or the foot? If you are using a cannula further away from the heart then a higher dose may well be needed as we need the adenosine to be active by the time it reaches the heart.
- Dose: we are always told to start at 100mcg/kg but actually the evidence shows most children need 170-200mcg/kg to revert. So if you are using IO access, or a cannula in the foot, then consider starting at 200mcg/kg.
- Drugs: theophylline competes at the adenosine receptor, so if you have a child who is on theophylline then you will need a higher dose.
- Diagnosis: patients in fascicular VT will not respond to adenosine and neither does Lown-Ganong-Levine syndrome.
Ah Tessa this is really so good! I love it. Im doing an ‘interactive paediatric cases’ presentation for F1-3 next week and one of my cases is a 1 year old with SVT. if you dont mind im going to pinch your infographics on treatment and adenosine 5Ds. I LOVE DFTB. thanks so much
Hi Shilpa – glad you like it! Of course – our content is FOAM so please feel free to use it and share it.
What is a rhythm strip and why is it necessary?
It’s a prolonged trace from a single lead, lasting 10 seconds, that is much more useful when examing arrhythmias than a shorter segment.
Hi Justin. It could be any cloth soaked in freezing cold water. It should be left on for 30-40 seconds which is longer than we usually dunk them for (not sure how long it’s been left on for when you’ve seen it tried with an ice bag)? Anything stimulating the cold receptors and covering the face should be fine – so optimal coverage at a low temperature is the goal. I’m going to try and see if there are any papers on this as my next task…
Great post. Just wondering if you could describe the face mask technique for the diving reflex in a little more detail. I’ve seen bags of ice on the face, which never seem to work, whereas the old and cruel dunking of the child is incredibly effective. I’m not sure what you are referring to as a face mask dipped in ice water.