Skip to content



Discitis is an inflammatory condition involving the intervertebral discs and end plates of vertebral bodies. It encompasses a spectrum of conditions that includes discitis, spondylodiscitis, and vertebral osteomyelitis.

Discitis is uncommon. However, there is a bimodal peak in children, those under 6 years and adolescents. Neonates can also be affected. Discitis most commonly occurs within the lumbar region, then thoracic and rarely cervical.

How does discitis present in children?

The presentation really depends on the age of the child.

  • Neonates – septic/irritable
  • 6 months – 6 years – non-specific limp, refusal to walk, back pain (often difficult to localise), low grade or no fever
  • >6 years – back pain (more localised), fever, generally unwell

The underlying pathology is usually infectious. A wide range of causative pathogens have been identified. In children, discitis is more likely to be due to haematogenous spread, though pathogens can be introduced directly during surgery or trauma. Discitis has also been reported as a very rare complication of button battery ingestion.

Discitis is often a result of inflammation secondary to a low-grade bacterial infection. Some authors believe that discitis is non-infectious in origin and actually the result of minor trauma. However, this can be difficult to prove, given how often young children bump into things.

Adults and children have different vasculature, and that might explain the different pathology. Vertebral discs vascularize during early childhood, with blood vessels appearing in the vertebral end plates by seven years of age. This allows direct haematogenous spread with the deposition of bacterial emboli within the disc itself. In older children, the subchondral spongy bone is supplied by end arteries. If septic emboli lodge there, they can cause bone infarction with vertebral osteomyelitis and subsequent extension through the endplate into the disc. Younger children tend to develop discitis first, and older children vertebral osteomyelitis.

Which organisms cause discitis?


  • Staphylococcus aureus – most common, present in up to 80% of cases in the first few months of life
  • Kingella kingae – an important cause of discitis in children aged 6 months – 4 years
  • Coagulase-negative Staph, Strep pneumoniae, Gram-negative rods, E.coli, Salmonella (important cause in patients with sickle cell disease)


  • Mycobacterium tuberculosis (Pott disease, predominantly in developing countries)
  • Brucella (unpasteurised goat cheese consumption)
  • Burkholderia
  • Fungi (Aspergillus, Candida, Cryptococcus) – immunosuppressed

What investigations should you consider?

Blood tests

  • WCC may be slightly elevated (higher in osteomyelitis cases)
  • CRP may be slightly elevated
  • ESR appears to be the most sensitive lab test, with levels commonly being moderately elevated

Blood cultures

  • Blood cultures are rarely positive. One study found 88% were sterile. But they can be very helpful if positive.
  • Needle aspiration/biopsies also have limited yield and are therefore reserved for atypical cases or when there is no response to first-line treatment. Some authors recommend isolation of an organism before commencing antimicrobial therapy.
  • Specific serology/PCR may be useful if cultures are negative


  • Plain radiographs can show abnormalities in up to 76% of patients. Findings include loss of disc space with erosion of the vertebral end plates. These features are delayed and not usually present until the disease has been present for 2-6 weeks.
  • MRI is the imaging modality of choice, with a sensitivity of 96% and specificity of 92%. It can reduce diagnostic delay and can identify adjacent inflammatory lesions requiring prolonged treatment +/- surgical intervention. It is also used to monitor improvement/resolution. Radiological resolution can take time.
Adapted from Alghamdi, A., 2016. Discitis in children. Neurosciences Journal21(3), pp.283-285.

How do you treat discitis in children?

Treatment is predominantly focused on bed rest, analgesia, and if possible, targeted anti-microbial therapy. If osteomyelitis is identified, it warrants antibiotic treatment (initially IV with subsequent step-down). The use of antibiotics in ‘sterile’ discitis is more controversial as there are case reports of spontaneous resolution. However, most authors recommend broad-spectrum IV antibiotics, adjusted when results are available, for a period of several days. There is no current consensus on duration. This can subsequently be stepped down to oral if there is a good response to immobilisation.


Brown R, Hussain M, McHugh K, Novelli V, Jones D. Discitis in young children. The Journal of Bone and Joint Surgery British volume. 2001 Jan;83-B.

Cottle L, Riordan T. Infectious spondylodiscitis. Journal of Infection. 2008 Jun;56.

Cushing AH. Diskitis in Children. Clinical Infectious Diseases. 1993 Jul 1;17(1). du Lac P, Panuel M, Devred P, Bollini G, Padovani J. MRI of disc space infection in infants and children. Pediatric Radiology. 1990 Jan;20.

Fernandez M, Carrol CL, Baker CJ. Discitis and Vertebral Osteomyelitis in Children: An 18-Year Review. PEDIATRICS. 2000 Jun 1;105.

Hensey OJ, Coad N, Carty HM, Sills JM. Juvenile discitis. Archives of Disease in Childhood. 1983 Dec 1;58.

Kieu V, Palit S, Wilson G, Ditchfield M, Buttery J, Burgner D, et al. Cervical Spondylodiscitis Following Button Battery Ingestion. The Journal of Pediatrics. 2014 Jun;164.

Langlois S, Cedoz JP, Lohse A, Toussirot E, Wendling D. Aseptic discitis in patients with ankylosing spondylitis: a retrospective study of 14 cases. Joint Bone Spine. 2005 May;72.

McNamara AL, Dickerson EC, Gomez-Hassan DM, Cinti SK, Srinivasan A. Yield of Image-Guided Needle Biopsy for Infectious Discitis: A Systematic Review and Meta-Analysis. American Journal of Neuroradiology. 2017 Oct;38.

Miranda I, Salom M, Burguet S. Discitis en niños menores de 3 años. Serie de casos y revisión de la literatura. Revista Española de Cirugía Ortopédica y Traumatología. 2014 Mar;58.

Modic MT, Feiglin DH, Piraino DW, Boumphrey F, Weinstein MA, Duchesneau PM, et al. Vertebral osteomyelitis: assessment using MR. Radiology. 1985 Oct;157.

Principi N, Esposito S. Infectious Discitis and Spondylodiscitis in Children. International Journal of Molecular Sciences. 2016 Apr 9;17.

Rudert M, Tillmann B. Lymph and blood supply of the human intervertebral disc: Cadaver study of correlations to discitis. Acta Orthopaedica Scandinavica. 1993 Jan 8;64.

Ventura N, Gonzalez E, Terricabras L, Salvador A, Cabrera M. Intervertebral discitis in children. International Orthopaedics. 1996 Feb 26;20.

Young A, Tekes A, Huisman TA, Bosemani T. Spondylodiscitis associated with button battery ingestion: prompt evaluation with MRI. The Neuroradiology Journal. 2015 Oct 12;28.


  • Elliott Habgood is a Paediatric Trainee in the East of England. He is interested in Paediatric Emergency Medicine and Medical Education and in his spare time enjoys hiking and playing or watching sports



Management of Button Battery Ingestion

, ,

Cervical Spine Imaging in Kids – the PECARN rule

, , ,

The ‘Hidden C’


Necrotising Enterocolitis

Copy of Trial (1)

Bubble Wrap PLUS – June 2024

Copy of Trial (1)

The 81st Bubble Wrap


Persistent Pulmonary Hypertension of the Newborn


Diagnosing acute post-streptococcal glomerulonephritis

Not a fever HEADER

When is a fever not ‘just a fever’?

Copy of Trial (1)

Bubble Wrap PLUS – May 2024

Copy of Trial (1)

The 80th Bubble wrap x DFTB MSc in PEM


SVT in infants




Paediatric acute respiratory distress syndrome (PARDS)

, ,

The Oxy-PICU trial

, , ,

Leave a Reply

Your email address will not be published. Required fields are marked *