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Steroids in Wheeze: Meredith Borland at DFTB18


This talk was recorded live at DFTB18 in Melbourne, Australia. With the theme of ‘Science and Story’, we pushed our speakers to step out of their comfort zones and consider why we do what we do. Caring for children is not just about acquiring scientific knowhow but also about looking beyond a diagnosis or clinical conundrum at the patient and their families.

Last year, at DFTB17, Katie Reeves started a conversation about managing wheeze in infancy. This year we were very privileged to have a world-leading researcher give us her take on it.

Meredith Borland is a founding member of the PREDICT collaborative and has led several key studies in paediatric emergency medicine. In this talk, she goes through the recent PREVIEW (Prednisolone Response Evaluation in Viral Induced Episodic Wheeze) study.

Foster SJ, Cooper MN, Oosterhof S, Borland ML. Oral prednisolone in preschool children with virus-associated wheeze: a prospective, randomised, double-blind, placebo-controlled trial. The Lancet Respiratory Medicine. 2018 Jan 17.

There are a number of controversies in managing preschool kids with wheeze, not least the challenge of making a diagnosis. Many parents might bring their child to the ED thinking their offspring has asthma. Still, bronchodilator-responsive wheeze is widespread, and not all these children go on to be formally diagnosed as asthmatic.

So what do we do in this middle group that doesn’t have bronchiolitis and doesn’t have asthma? Listen to Meredith Borland to find out what she recommends.

Meredith Borland with Arjun Rao

Tessa wrote about steroids for pre-school wheeze here and had a chat about them with Ken Milne on episode #206 of the SGEM.

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