Nitric oxide

Cite this article as: Anders, M. Nitric oxide, Don't Forget the Bubbles, 2013. Available at: http://doi.org/10.31440/DFTB.3693Definition: nitric oxide (NO) is produced in the endothelium by eNOS (endothelial nitric oxide synthase).

Heart transplantation

Heart transplantation

Uncategorized

Cite this article as: Anders, M. Heart transplantation, Don't Forget the Bubbles, 2013. Available at: http://doi.org/10.31440/DFTB.3669Indication: life expectancy <2 years and/or unacceptable quality of life, end stage CHD, DCM, HCM (see cardiomyopathy) Risk profile: PVR (low risk: PVR ≤4 WU or TPG ≤10 mmHg, medium risk: PVR 5-9 WU or TPG 10-20 mmHg) High risk/contraindicated: PVR >9…

Myocarditis

Cite this article as: Anders, M. Myocarditis, Don't Forget the Bubbles, 2013. Available at: http://doi.org/10.31440/DFTB.3794See cardiomyopathy , but cardiac MRI or endomyocardial biopsy to confirm diagnosis Symptoms:  Very nonspecific in children: malaise, fever, poor appetite, tachypnea, tachycardia, chest pain, abdominal pain, myalgia, fatigue, cough, oedema, hepatomegaly, murmur. Investigations: See also cardiomyopathy Nonspecific T changes on ECG…

Heart failure and ventricular assist device (VAD)

Cite this article as: Anders, M. Heart failure and ventricular assist device (VAD), Don't Forget the Bubbles, 2013. Available at: http://doi.org/10.31440/DFTB.3790Modified Ross heart failure classification: Class Symptoms I Asymptomatic II Mild tachypneoa or diaphoresis with feeding. Dyspnea on exertion in older children III Marked tachypnea or diaphoresis with feeding; marked dyspnea on exertion; prolonged feeding time with…

ECMO antibiotics

Cite this article as: Anders, M. ECMO antibiotics, Don't Forget the Bubbles, 2013. Available at: http://doi.org/10.31440/DFTB.3783 Indication Prophylaxis Timing Duration ECMO (cannulation, chest revision, reoperation on ECMO, decannulation) – if not on anitbiotics with both gramnegative and grampositive cover already Cephazolin 50mg/kg up to 1g IV or (if cephazolin unavailable)Cephalothin 50mg/kg up to 2g IV Optimal timing for…

ECMO

Cite this article as: Anders, M. ECMO, Don't Forget the Bubbles, 2013. Available at: http://doi.org/10.31440/DFTB.3778Inclusion criteria: >34/40 weeks gestation age, reversible cardiac, pulmonary, or cardiopulmonary failure, mechanical ventilation <14 days. Exclusion criteria: Major intracranial haemorrhage, lethal malformation, severe neurological injury, untreatable cardiac or pulmonary malformation. Clinical indications: Failure to wean off cardiopulmonary bypass, oxygenation index…