Guanfacine

On 22nd August 2017, guanfacine hydrochloride (current sole brand name Intuniv) was accepted as a new chemical entity by the Therapeutic Goods Administration in Australia.1 Whilst new to Australia, guanfacine has been available within the United States of America and Europe since 20102 and 20153 respectively. The development of generic brands within these countries has…

Schrodinger’s PANDAS

The existence of PANDAS and other Paediatric Acute Onset Neuropsychiatric Syndromes has been controversial for the last two decades. What is PANDAS? Paediatric Acute-Onset Neuropsychiatric Disorder Associated with Streptococcal infection, is a concept first mooted by Swedo, an American paediatrician in 1998, as a formé fruste (or incomplete form) of Sydenhams Chorea. Swedo SE, Leonard…

Adolescent Inpatient Psychiatry

I’ve been lucky enough to be one of the few paediatric registrars allocated to an Adolescent Inpatient Mental Health ward for a 6 month rotation. Although I’d worked in (adult) Psych wards before, I had few well formed ideas about psychiatric theory or practice past how to “do a takedown”. In Shem’s House of God,…

Big Picture Paediatrics : Adverse Childhood Experiences

So much of paediatrics, and medicine in general, is focussed on small experimental or observational studies. This series of posts takes the wider view; we’re talking here about some of the biggest and longest running studies that help us frame, measure and understand childhood through time and across the world. References: Felitti, VJ, Anda RF,…

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