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Here is a new Bubble Wrap Plus, our monthly paediatric Journal Club List provided by Professor Jaan Toelen of the University Hospitals in Leuven (Belgium). This comprehensive list of ‘articles to read’ comes from 34 journals, including Pediatrics, The Journal of Pediatrics, Archives of Disease in Childhood, JAMA Pediatrics, Journal of Paediatrics and Child Health, NEJM, and many more. This month’s list is an anniversary list! The list exists for 10 years… And hopefully many more to come. There is also an April fool’s day link included – can you find it? 

Prof. Jaan Toelen

This month’s list features answers to intriguing questions such as: ‘Can AI help in the diagnosis of otitis media or ROP?’, ‘Can fathers influence the duration of breastfeeding?’, ‘Does a high milk intake correlate with iron deficiency?’, ‘What are the best nonpharmacological interventions for migraine?’ and ‘Do doctors need sleep?’.

You will find the list is broken down into four sections:

1.Reviews and opinion articles

2.Original clinical studies

Machine Learning for Accurate Intraoperative Pediatric Middle Ear Effusion Diagnosis.

Crowson MG, et al. Pediatrics. 2021 Mar 17:e2020034546

Can Machine Learning and AI Replace Otoscopy for Diagnosis of Otitis Media?

Pichichero ME. Pediatrics. 2021 Mar 17:e2020049584

Applications of Artificial Intelligence for Retinopathy of Prematurity Screening.

Campbell JP, et al. Pediatrics. 2021 Mar;147(3):e2020016618. 

Artificial Intelligence for ROP Screening and to Assess Quality of Care: Progress and Challenges.

Gilbert C, et al. Pediatrics. 2021 Mar;147(3):e2020034314. 

From dyad to triad: a survey on fathers’ knowledge and attitudes toward breastfeeding.

Crippa BL, et al. Eur J Pediatr. 2021 Mar 29. 

Breastfeeding patterns and effects of minimal supplementation on breastfeeding exclusivity and duration in term infants: A prospective sub-study of a randomised controlled trial.

Bond DM, et al. J Paediatr Child Health. 2021 Mar 25. 

Does cystic fibrosis make susceptible to celiac disease?

Emiralioglu N, et al. Eur J Pediatr. 2021 Mar 25. 

Clinical, sonographical, and pathological findings of pediatric thyroid nodules.

Cimbek EA, et al. Eur J Pediatr. 2021 Mar 26. 

Association of Race/Ethnicity and Social Disadvantage With Autism Prevalence in 7 Million School Children in England.

Roman-Urrestarazu A, et al. JAMA Pediatr. 2021 Mar 29:e210054. 

Vaccine hesitancy and reported non-vaccination in an Irish pediatric outpatient population.

Whelan SO, et al. Eur J Pediatr. 2021 Mar 27. 

Respiratory Virus Surveillance in Infants Across Different Clinical Setting.

Haddadin Z, et al. J Pediatr. 2021 Mar 24:S0022-3476(21)00274-2. 

Cutting Ties With an Old Friend: Omphalitis and Bacteremia With Umbilical Cord Nonseverance.

Lanni L, et al. Pediatrics. 2021 Mar 26:e2020008938. 

Clinical Epidemiology and Outcomes of Pediatric Musculoskeletal Infections.

Yi J, et al. J Pediatr. 2021 Mar 23:S0022-3476(21)00266-3. 

Gestational hypertension and childhood atopy: a Millennium Cohort Study analysis.

Henderson I, et al. Eur J Pediatr. 2021 Mar 26. 

Association Between Hypertensive Disorders of Pregnancy and Neurodevelopmental Outcomes Among Offspring.

Brand JS, et al. JAMA Pediatr. 2021 Mar 22. 

Self-Inflicted Dermatoses In Adolescence: A Case Series.

Sarti L, et al. J Paediatr Child Health. 2021 Mar 25. 

Contamination rates of different methods of urine culture collection in children: A retrospective cohort study.

Guri A, et al. J Paediatr Child Health. 2021 Mar 24. 

Prevalence and associated factors of iron deficiency in Spanish children aged 1 to 11 years.

López-Ruzafa E, et al. Eur J Pediatr. 2021 Mar 23. 

The influence of chest X-ray results on antibiotic prescription for childhood pneumonia in the emergency department.

van de Maat JS, et al. Eur J Pediatr. 2021 Mar 22. 

Short- Versus Prolonged-Duration Antibiotics for Outpatient Pneumonia in Children.

Shapiro DJ, et al. J Pediatr. 2021 Mar 18:S0022-3476(21)00231-6. 

Rightsizing Treatment for Pneumonia in Children.

Tsay SV, et al. JAMA Pediatr. 2021 Mar 8. 

Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial.

Pernica JM, et al. JAMA Pediatr. 2021 Mar 8:e206735. 

Acute kidney injury in children hospitalized for community acquired pneumonia.

Marzuillo P, et al. Pediatr Nephrol. 2021 Mar 20. 

Higher-Calorie Refeeding in Anorexia Nervosa: 1-Year Outcomes From a Randomized Controlled Trial.

Golden NH, et al. Pediatrics. 2021 Mar 22:e2020037135. 

Prior administration of chocolate improves the palatability of bitter drugs: The Choc-with-Med study.

Truong S, et al. J Paediatr Child Health. 2021 Mar 19

Family and Child Risk Factors for Early-Life RSV Illness.

Fitzpatrick T, et al. Pediatrics. 2021 Mar 18:e2020029090. 

Early Life RSV: Can Vaccines Help Fix Societal Ills?

Caserta MT, et al. Pediatrics. 2021 Mar 18:e2020038356. 

Effect of a Novel Oxygen Saturation Targeting Strategy on Mortality, Retinopathy of Prematurity and Bronchopulmonary Dysplasia in Extremely Preterm Neonates.

Srivatsa B, et al. J Pediatr. 2021 Mar 15:S0022-3476(21)00219-5. 

Influence of agents and mechanisms of injury on anatomical burn locations in children <5 years old with a scald.

Javaid AA, et al. Arch Dis Child. 2021 Mar 16:archdischild-2020-320710. 

A Brief Home-Based Parenting Intervention to Reduce Behavior Problems in Young Children: A Pragmatic Randomized Clinical Trial.

O’Farrelly C, et al. JAMA Pediatr. 2021 Mar 15. 

Ingestion of metallic foreign bodies: A Paediatric Emergency Research in the United Kingdom and Ireland survey of current practice and hand-held metal detector use.

Lafferty M, et al. J Paediatr Child Health. 2021 Mar 15. 

Nonpharmacological Interventions for Pediatric Migraine: A Network Meta-analysis.

Koechlin H, et al. Pediatrics. 2021 Mar 9:e20194107. 

Leukemia Risk in a Cohort of 3.9 Million Children With and Without Down Syndrome.

Marlow EC, et al. J Pediatr. 2021 Mar 5:S0022-3476(21)00212-2. 

Incidence of allergen-specific and total immunoglobulin E positivity in children undergoing adenotonsillectomy.

Lam ME, et al. J Paediatr Child Health. 2021 Mar 8. 

Rectum sizes: Assessment by ultrasonography in children with functional constipation.

Pop D, et al. J Paediatr Child Health. 2021 Mar 4

Evaluation of Fecal Incontinence in Pediatric Functional Constipation: Clinical Utility of Anorectal and Colon Manometry.

Morera C, et al. J Pediatr Gastroenterol Nutr. 2021 Mar 1;72(3):361-365. 

Neonatal morbidities in infants born late preterm at 35-36 weeks of gestation – a Swedish nationwide population-based study.

Mitha A, et al. J Pediatr. 2021 Mar 1:S0022-3476(21)00205-5. 

Uncertainty at the Limits of Viability: A Qualitative Study of Antenatal Consultations.

Kaemingk BD, et al. Pediatrics. 2021 Mar 3:e20201865. 

Clinical presentations of Kingella kingae musculoskeletal infections in South Australian children.

Awwad E, et al. J Paediatr Child Health. 2021 Mar 3

Oropharyngeal Carriage of Kingella kingae and Transient Synovitis of the Hip in Young Children: A Case-control Study.

Gravel J, et al. Pediatr Infect Dis J. 2021 Mar 1;40(3):182-185. 

Are psychological symptoms a risk factor for musculoskeletal pain in adolescents?

Andreucci A, et al. Eur J Pediatr. 2021 Mar 2. 

Adverse events associated with pediatric complementary and alternative medicine in the Netherlands: a national surveillance study.

Vos B, et al. Eur J Pediatr. 2021 Mar 1. 

Intermittent vs Continuous Pulse Oximetry in Hospitalized Infants With Stabilized Bronchiolitis: A Randomized Clinical Trial.

Mahant S, et al. AMA Pediatr. 2021 Mar 1:e206141. 

Should We Prioritize Deimplementation of Continuous Pulse Oximetry in Bronchiolitis Care?

Cheston CC, et al. JAMA Pediatr. 2021 Mar 1

Doctors Also Need Sleep: Is It Time to Take Another Look at Our ROSTERS?

Dairo Oguntebi A, et al. Pediatrics. 2021 Mar;147(3):e2020034017. 

Extended Work Shifts and Neurobehavioral Performance in Resident-Physicians.

Rahman SA, et al. Pediatrics. 2021 Mar;147(3):e2020009936. 

Childhood and Adolescent Bullying Perpetration and Later Substance Use: A Meta-analysis.

Vrijen C, et al. Pediatrics. 2021 Mar;147(3):e2020034751. 

Puberty Is Associated with a Rising Hemoglobin A1c, Even in Youth with Normal Weight.

Kelsey MM, et al. J Pediatr. 2021 Mar;230:244-247. 

Effect of Antibiotic Use Within First 48 Hours of Life on the Preterm Infant Microbiome: A Randomized Clinical Trial.

Kim CS, et al. JAMA Pediatr. 2021 Mar 1;175(3):303-305. 

Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19.

Feldstein LR, et al. JAMA. 2021 Mar 16;325(11):1074-1087. 

COVID-19 and primary immunodeficiency: One-year experience.

Al Yazidi LS, et al. J Paediatr Child Health. 2021 Mar 10. 

Cardiorespiratory fitness in adolescents before and after the COVID-19 confinement: a prospective cohort study.

López-Bueno R, et al. Eur J Pediatr. 2021 Mar 17:1-7. 

Bronchiolitis Admissions to Intensive Care During COVID.

Rambaud J, et al. Pediatrics. 2021 Mar 17:e2021050103

Bronchiolitis and SARS-CoV-2.

Milani GP, et al. Arch Dis Child. 2021 Mar 11:archdischild-2020-321108

The impact of lockdown on pediatric ED visits and hospital admissions during the COVID19 pandemic: a multicenter analysis and review of the literature.

Kruizinga MD, et al. Eur J Pediatr. 2021 Mar 15:1-9

COVID-19 related increase in childhood tics and tic-like attacks.

Heyman I, et al. Arch Dis Child. 2021 Mar 6:archdischild-2021-321748. 

Infants Born to Mothers With COVID-19-Making Room for Rooming-in.

Kaufman DA, et al. JAMA Pediatr. 2021 Mar 1;175(3):240-242. 

Evaluation of Rooming-in Practice for Neonates Born to Mothers With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Italy.

Ronchi A, et al. JAMA Pediatr. 2021 Mar 1;175(3):260-266. 

4.Case reports

A 9-year-old boy with severe motor and intellectual disabilities and prolonged abdominal distension.

Higuchi Y, et al. J Paediatr Child Health. 2021 Mar 26. 

Severe acute anaemia in an infant: An unusual finding.

Nogueira A, et al. J Paediatr Child Health. 2021 Mar 27. 

‘Starry sky’ rash in a child.

Conversano E, et al. J Paediatr Child Health. 2021 Mar 16. 

Adolescent with right axillary swelling.

Trombetta A, et al. J Paediatr Child Health. 2021 Mar 24

A 17-year-old With Trismus and Neck Pain.

Vatansever G, et al. Pediatr Infect Dis J. 2021 Mar 16. 

Hiding in plain sight: A case of lower abdominal pain.

Scheier E, et al. J Paediatr Child Health. 2021 Mar 4. 

Behavioural changes in an adolescent boy: Not always as it seems.

Linhares RE, et al. J Paediatr Child Health. 2021 Mar 17. 

If we have missed out on something useful or you think other articles are absolutely worth sharing, please add them in the comments!

About the authors

  • Anke is a paediatrician from Belgium, currently working in Antwerp (ZNA Jan Palfijn, Belgium) after completing her fellowship at the Sydney Children’s Hospital. She is passionate about education, teaching, and research and has completed a PhD on health outcomes of preterm infants. Anke strongly believes in the importance of evidence-based medicine, helping to run journal clubs everywhere she works and BubbleWrapPlus. In her free time, she loves to hike with her husband and three kids.

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