Empiric antibiotics for general infection

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Cite this article as:
Anders, M. Empiric antibiotics for general infection, Don't Forget the Bubbles, 2013. Available at:
http://doi.org/10.31440/DFTB.3846
Age if meningitis excluded if meningitis is NOT excluded if Staphylococcus aureus suspected
< 3 months Amoxicillin 50 mg/kg q6hrGentamycin 7.5 mg/kg q24hr Amoxicillin 50 mg/kg q6hrGentamycin 7.5 mg/kg q24hr

Cefotaxime 50 mg/kg q6hr

Consider especially in infants aciclovir 20mg/kg q8hr

Amoxicillin 50 mg/kg q6hrCefotaxime 50 mg/kg q6hr

Vancomycin 15 mg/kg q6hr

Clindamycin 15 mg/kg q8hr

> 3 months Cefotaxime 50 mg/kg q6hrFlucloxacillin 50 mg/kg q4-6hr Cefotaxime 50 mg/kg q6hrFlucloxacillin 50 mg/kg q4-6hr Cefotaxime 50 mg/kg q6hrVancomycin 15 mg/kg q6hr

Clindamycin 15 mg/kg q8hr

any age group, if immuno-compromised Meropenem 20 mg/kg IV q8hrVancomycin 15 mg/kg q6hr

Gentamycin 7.5 mg/kg q24hr

if Meningitis is NOT excluded, and suspicion of severe Meningitis (gram stain), replace Flucloxacillin by Vancomycin 15 mg/kg q6hr to cover for Penicillin resistant Pneumococcus Meningitis 
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Marc Anders is a paediatric intensivist.

Author: Marc Anders Marc Anders is a paediatric intensivist.

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