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Don’t Forget the Brain Busters – Round 2


The Bubble Wrap Treasure Hunt Round

This round is an excellent excuse to go on a hunt through some studies we think are pretty important.


Q1: Freedman et al conducted a study of the management of gastroenteritis – apple juice was found to have fewer treatment failures than electrolyte maintenance solution. But how many of the recruited 647 children actually had evidence of dehydration?

A: 85 (13.1%)
B: 206 (31.8%)
C: 324 (50.0%)
D: 400 (61.8%)
E: 512 (79.1%0


Q2: Maitland et al conducted the groundbreaking FEAST study examining different fluid regimes for the management of sepsis. How many children in TOTAL (of 3141 randomized) had severe hypotension (a systolic less than 50mmHg in <12 months old, <60mmHg in 1-5 year olds, <70mmHg in older than 5-year-olds plus one or more feature of impaired perfusion)?

A: 6
B: 58
C: 234
D: 789
E: 1899


Q3: Cunningham et al conducted the influential BIDS study which assessed whether the 90% or higher target for management of oxygen supplementation was equivalent to a normoxic 94% or higher target for infants admitted to hospital with viral bronchiolitis. What was the primary outcome measure?

A: Length of stay on a paediatric ward
B: Length of stay in intensive care
C: Number of days on oxygen
D: Time to resolution of cough
E: Escalation to high flow or CPAP therapy


Q4: Winter et al conducted a 4 year retrospective review of 33185 children. How many adverse events were there in children discharged with at least one abnormal vital sign?

A: None
B: 24
C: 314
D: 1024
E: 3987


Q5. Bexkens et al conducted a meta-analysis of pulled elbows. How many patients do you have to treat with hyper-pronation for a benefit over supination-flexion to be demonstrated?

A: 1
B: 4
C: 11
D: 300
E: 1000

See the answers here: Round 2 answers


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2 thoughts on “Don’t Forget the Brain Busters – Round 2”

  1. Hi Folks,
    Do we get extra points for noting that Bexkens actually made an error in their calculation which they corrected in a subsequent submission to the journal, changing the NNT to 5.5?? 😉



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